Nicotine affects fertility and this is clearly stated in the health warning printed on cigarette packs.

In fact the effect of smoking on a woman's fertility is more serious than previously thought. The fertility of a woman smoker is the same as the fertility of a non-smoking woman 10 years older. An article published in “Human Reproduction” observed a 28% lower rate of the “baby-take-home-rate” in women smokers than in their non-smoking peers.